Sir Aaron Klug

Born on August 11, 1926.

British biochemist who received the 1982 Nobel Prize in Chemistry «for the development of the crystallographic electron microscope and the elucidation of the structure of the important nucleic acid-protein complexes. biologically important.” While X-ray diffraction patterns reveal any highly ordered three-dimensional crystal structures, this technique fails for biological samples with less well-ordered molecular structures. However, Klug developed a crystal electron microscope that combined certain principles of diffraction with electron microscopy so that he could find the 3-D structure of the virus or the resulting patterns. complex of nucleic acids and proteins as found in membranes, muscle fibers and chromosomes.