British physiologist and co-inventor of the prone pressure artificial respiration method adopted by the Royal Life Saving Society. In 1894 Sharpey-Schafer demonstrated the effect of a particular hormone (adrenaline, an extract of the adrenal gland) on blood vessels and muscle contraction. They also noted that the smooth muscles of the animal’s bronchi were relaxed. His work aroused interest in studying the nature and function of hormones. Sharpey-Schafer also suspected that another hormone was being produced by the islets of Langerhans in the pancreas.