Acrodermatitis enteropathica

  • A rare disorder is associated with zinc deficiency.
  • The classic triad of Peri-acral and periorificial dermatitis+ Diarrhoea &Alopeci
  • Primary: inherited zinc transporter defect, resulting in reduced intestinal absorption of zinc (Danbolt-Closs syndrome, and Brandt syndrome)
  • Secondary: Acquired due to reduced intake, increased demand, malabsorption, or may rarely be associated with certain metabolic disorders.

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