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Polycystic kidney disease (PKD)

  • Polycystic kidney disease (PKD). is classified into 2 distinct disorders: autosomal recessive PKD (ARPKD ) and autosomal dominant PKD (ADPKD).
  • ARPKD: inherited mutation of PKD1 (polycystin-1) or PKD2 (polycystin-2) genes à severe pulmonary insufficiency and progressive renal failure with onset during infancy or early childhood
  • ADPKD: inherited mutation in the PKHD1 gene à arterial hypertension, flank pain,and progressive kidney disease with onset in adulthood.


Jun 17 2022


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