Hyperpituitarism

  • Gigantism: growth hormone hypersecretion occurs before epiphysial fusion,
  • Acromegaly: growth hormone hypersecretion occurs after puberty (growth plates have fused) only flat bone enlargement and soft tissue growth are possible.
  • Characteristic hand features:
  • Enlargement of Hands and Feet
  • Pachydermia: thickening of the skin and connective tissue

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