Toxic epidermal necrolysis (TEN)

  • Essentials of Dx: Toxic epidermal necrolysis (TEN)
    • Stevens-Johnson syndrome vs toxic epidermal necrolysis
      • Stevens-Johnson syndrome: Less than 10% BSA detachment.
      • Stevens-Johnson syndrome/toxic epidermal necrolysis overlap: 10–30% BSA detachment.
      • Toxic epidermal necrolysis: Greater than 30% BSA detachment.
    • Medications are the most common cause.
    • Cutaneous lesions are targetoid but often not true three-ring targets.
    • Favors the trunk.
    • Involves two or more mucous membranes.
    • May progress to significant BSA involvement and may be life-threatening.
  • Reference from CMDT (61st Ed), Pg no: 135

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